ADOLPH B. LOVEMAN, A.B., M.D.
Senator77 in 1888 reported four fatal cases of acute infectious pharyngitis. Unfortunately no bacteriological or hematological studies were made. Fourteen years later Brown70 reported the first case of acute infectious pharyngitis with complete blood studies. The patient showed a marked leukopenia and on one occasion the polymorphonuclears were reduced to one per cent. From then until Schultz75 reported his cases of agranulocytic angina, examples of an agranulocytic blood picture were described by Schwartz,73 Türk,72 and Marchand.74
As early as 1920, Moore and Foley7 reported agranulocytic blood pictures following the arsphenamines. Since then many cases have been added to the literature.
LOVEMAN AB. Toxic Granulocytopenia, Purpura Hemorrhagica and Aplastic Anemia Following the Arsphenamines12. Ann Intern Med. ;5:1238–1256. doi: 10.7326/0003-4819-5-10-1238
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Published: Ann Intern Med. 1932;5(10):1238-1256.
Coagulopathies, Hematology/Oncology, Red Cell Disorders.
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