W. C. WATERS, M.D.
Unsatisfactory restoration of function so frequently follows surgical amputations for the gangrene of peripheral vascular diseases that interest in the treatment of such disturbances has been revived. Samuels1 views the gangrene in these conditions as a self-limiting process and recommends conservatism until so much tissue has been destroyed that nonfunction appears to be inevitable.
Among palliative measures which have proved beneficial may be mentioned postural exercises,2 the use of Ringer's solution by duodenal tube and by hypodermoclysis,3 and the intravenous administration of sodium citrate4 and sodium iodide solution.5
In 1926, Brown6 introduced the use of typhoid vaccine given intravenously to
WATERS WC. Peripheral Vascular Diseases: Treatment with Acetyl-choline Hydrochloride1. Ann Intern Med. ;5:1267–1273. doi: 10.7326/0003-4819-5-10-1267
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Published: Ann Intern Med. 1932;5(10):1267-1273.
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