EDGAR R. PUND, A.B., M.D., F.A.C.P.; THOMAS B. PHINIZY, M.D.
Arteriosclerosis of the pulmonary artery may be primary or secondary. The primary type is rare and affects the small arteries and the arterioles of the pulmonary circulation with or without accompanying arteriosclerotic changes in the larger branches. The sclerotic changes in the small arteries produce narrowing and even obliteration of the lumen, thereby causing an increase in the pulmonary blood pressure, followed by dilation and hypertrophy of the right side of the heart and finally cardiac failure. There are no antecedent pulmonary or cardiac changes, and, according to Steinberg,1 the use of the term primary sclerosis of the pulmonary artery
PUND ER, PHINIZY TB. Primary Sclerosis of the Pulmonary Artery12: Report of a Case. Ann Intern Med. ;5:1391–1396. doi: 10.7326/0003-4819-5-11-1391
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Published: Ann Intern Med. 1932;5(11):1391-1396.
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