FRANCIS D. MURPHY, M.S., M.D., F.A.C.P.; JOHN GRILL, M.D.; BENJAMIN PESSIN, B.S., M.D.; GAIL F. MOXON, A.B., M.D.
The variety of symptoms and vascular lesions associated with essential hypertension is so great that consecutive stages of the disorder may appear at times to be diseases of different kinds. Most cases of essential hypertension conform to the usually well recognized course of chronic hypertension which terminates, after years, in heart failure, cerebral hemorrhage, renal failure or some intercurrent infection. But there is a small group of cases, which, because of the peculiarities of the symptoms and vascular lesions, has been set aside by some observers in a separate class and designated "malignant" hypertension. Over the pathogenesis of the arteriolar
MURPHY FD, GRILL J, PESSIN B, MOXON GF. Essential (Primary) Hypertension: A Clinical and Morphological Study of 375 Cases12. Ann Intern Med. ;6:31–53. doi: 10.7326/0003-4819-6-1-31
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Published: Ann Intern Med. 1932;6(1):31-53.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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