WILLIAM S. MIDDLETON, M.D., F.A.C.P.
The bald tongue has been recognized for many years by clinicians. Its association with anemia was probably first appreciated in 1846 by Dawson.1 In 1909 William Hunter2 concluded an argument for the infectious origin of the glossitic, gastric and intestinal lesions of pernicious anemia with the statement "that the most important of these sign-posts (glossitic) is the one which can be earliest recognized and kept in sight from the first to the last". The strength of this position was universally conceded by students of the subject; but renewed interest in and attention to the close scrutiny of the tongue in
MIDDLETON WS. The Clinical Study of the Atrophic Tongue. Ann Intern Med. 1932;6:352–361. doi: 10.7326/0003-4819-6-3-352
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Published: Ann Intern Med. 1932;6(3):352-361.
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