R. L. BENSON, A.M., M.D., F.A.C.P.
As early as the beginning of the present century the late Victor C. Vaughan1 already had an adequate understanding of the problems of bacterial sensitization. This eminent biochemist maintained that bacteria, although morphologically simple in structure, are correspondingly complicated in their chemistry and comprise in particular a group of highly complex proteins. His insight into the minute chemistry of bacteria is further evidenced by his account of one or more carbohydrate components which he regarded as intimately linked with the large nucleoprotein molecules. He concluded that these constituents could readily be split apart by dilute acid or alkali, but better
BENSON RL. The Rôle of Bacteria in Allergy, with Special Reference to Asthma1. Ann Intern Med. ;6:1136–1152. doi: 10.7326/0003-4819-6-9-1136
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Published: Ann Intern Med. 1933;6(9):1136-1152.
Asthma, Infectious Disease, Pulmonary/Critical Care.
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