JOHN F. KESSEL; EDYTHE J. ROSE
Since the suggestion was first made that bacteriophage be used as a therapeutic agent, numerous reports have occurred in medical literature concerning its value. Some of them have been favorable in character, and others less certain as to its beneficial effects. Bacteriophage has been recommended for a great variety of conditions and, indeed, possesses the characteristics required of an ideal germicide in that it is harmless to the body tissues and theoretically destroys the pathogenic organisms. This phenomenon of lysis can be demonstrated easily in vitro with young cultures, but it is doubtful if the results obtained in the
KESSEL JF, ROSE EJ. Bacteriophage Therapy in Bacillary Dysentery of the Flexner Type12. Ann Intern Med. ;6:1193–1199. doi: 10.7326/0003-4819-6-9-1193
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Published: Ann Intern Med. 1933;6(9):1193-1199.
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