J. LERMAN, M.D.; R. J. CLARK, M.D.; J. H. MEANS, M.D., F.A.C.P.
In various articles and textbooks dealing with myxedema, very little has been said regarding the heart. The literature covering the subject of the heart in myxedema is marked by paucity, contradiction, and confusion.
In 1918 Zondek1 introduced the term "myxedema heart" and described its characteristics as follows:
I. Before treatment with thyroid.
1. Dilatation of the left and right heart which may be of a very high degree.
2. Slow, indolent heart action with normal blood pressure.
3. Lowering of the auricular wave and the T-wave of the electrocardiogram.
II. Following treatment with thyroid.
LERMAN J, CLARK RJ, MEANS JH. The Heart in Myxedema12: Electrocardiograms and Roentgen-Ray Measurements before and after Therapy. Ann Intern Med. ;6:1251–1271. doi: 10.7326/0003-4819-6-10-1251
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Published: Ann Intern Med. 1933;6(10):1251-1271.
Cardiac Diagnosis and Imaging, Cardiology, Endocrine and Metabolism, Thyroid Disorders.
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