WALTER K. GRIGG, M.D.; VICTOR C. JACOBSEN, M.D.
Cinchophen was first introduced to therapeutics in 1908 by Nicolaier and Dohrn for the treatment of gout. Since then its use has been extended to arthritis in general and as an analgesic. Various closely allied chemical compounds and derivatives have been brought out from time to time until now there are many similar drugs on the market, and with the multiplicity of trade names it is doubtful whether persons using or prescribing them are fully acquainted with the toxicity which they possess. Rabinowitz1 has listed twenty in this group of remedies, and there are probably others.
The toxicity of these
GRIGG WK, JACOBSEN VC. Subacute Yellow Atrophy of the Liver Following Ingestion of Cinchophen and Allied Compounds12. Ann Intern Med. 1933;6:1280–1288. doi: 10.7326/0003-4819-6-10-1280
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Published: Ann Intern Med. 1933;6(10):1280-1288.
Gastroenterology/Hepatology, Liver Disease.
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