A. R. FREEMAN, M.D.; SAMUEL A. LEVINE, M.D., F.A.C.P.
The significance of the systolic heart murmur has long been a matter of considerable discussion. Not so very long ago, if a heart murmur was heard in a patient, the physician would quickly make a diagnosis of some organic heart condition. If it were systolic in time, and especially if apical in origin, a diagnosis of mitral insufficiency would be made. About fifteen years ago, particularly as a result of the extensive experience with neurocirculatory asthenia, or the so-called soldier's heart during the great war, the pendulum began to swing to the diametrically opposite position. It was found that
FREEMAN AR, LEVINE SA. The Clinical Significance of the Systolic Murmur12: A Study of 1000 Consecutive "Non-Cardiac" Cases. Ann Intern Med. 1933;6:1371–1385. doi: 10.7326/0003-4819-6-11-1371
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Published: Ann Intern Med. 1933;6(11):1371-1385.
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