ARTHUR D. GOLDHAFT, V.M.D.; LILLIE M. WRIGHT, M.A.; RALPH PEMBERTON, M.D., F.A.C.P.
In a previous communication, evidence has been adduced by the present writers which indicates that it is possible to induce an overgrowth in the patella of dogs, characteristic of hypertrophic arthritis, by ligation of the blood supply to that structure. The changes resulting consisted in a marked increase in size of the patella which reached its maximum about nine months after operation. Control experiments showed that this result was not due to the trauma of operative procedure. The phenomena accompanying overgrowth were essentially those characterizing hypertrophic arthritis as seen in human beings, but there were also some evidences of atrophic
GOLDHAFT AD, WRIGHT LM, PEMBERTON R. The Influence of Age in the Experimental Production of Hypertrophic Arthritis1: Preliminary Report. Ann Intern Med. ;6:1591–1598. doi: 10.7326/0003-4819-6-12-1591
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Published: Ann Intern Med. 1933;6(12):1591-1598.
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