ZACHARY SAGAL, M.D.; JEROME A. MARKS, M.D.; JOHN L. KANTOR, M.D.
In 1886, Jaworski and Gluzinski1 introduced the generally accepted system of estimating gastric acidity in terms of "degrees." They then pointed out that the subject had been intensively studied for over a hundred years and apologized for adding another communication to the many already published. Forty-six years later, Vanzant and her collaborators2 called attention to the amazing fact that, despite the enormous amount of investigation, we have not even today any reliable standards of normal acidity for various ages. Their explanation that this gap in our knowledge is due in part to the difficulty of getting a large number of
SAGAL Z, MARKS JA, KANTOR JL. THE CLINICAL SIGNIFICANCE OF GASTRIC ACIDITY1: A Study of 6679 Cases with Digestive Symptoms. Ann Intern Med. ;7:76–88. doi: 10.7326/0003-4819-7-1-76
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Published: Ann Intern Med. 1933;7(1):76-88.
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