ERNEST H. FALCONER, M.D., F.A.C.P.
Venesection was formerly frequently employed as a therapeutic measure in the treatment of polycythemia, but its results have not been systematically studied. It has usually been considered as a measure of expediency rather than one of real value in the treatment of this condition. One of the present common objections to its use is based on the premise that repeated bleeding stimulates the bone marrow excessively, tending to premature exhaustion.
It was to test the validity of this premise, as applied to polycythemia vera, that this study was undertaken. The administration of phenylhydrazin hydrochloride by mouth, or radiation over spleen
FALCONER EH. TREATMENT OF POLYCYTHEMIA: THE RETICULOCYTE RESPONSE TO VENESECTION, PHENYLHYDRAZIN AND RADIATION1. Ann Intern Med. ;7:172–189. doi: 10.7326/0003-4819-7-2-172
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Published: Ann Intern Med. 1933;7(2):172-189.
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