OSCAR RICHTER, M.D.; ARTHUR E. MEYER, PH.D.; ANDREW C. IVY, M.D., PH.D., F.A.C.P.
Recently we1 have reported that excellent remissions can be obtained in pernicious anemia patients with low blood counts from the subcutaneous or intravenous injections of a potent, highly purified horse liver extract. This communication entails a report of our observations on the further use of this injectable liver extract in 46 patients with pernicious anemia, covering a period of one year, during which time several thousand injections were given without local or systemic reaction. Although the oral administration of whole liver, liver extracts, and stomach substance are of unquestionable value in the treatment and maintenance of patients with pernicious anemia,
RICHTER O, MEYER AE, IVY AC. FURTHER OBSERVATIONS ON THE TREATMENT OF PERNICIOUS ANEMIA WITH PARENTERAL HORSE LIVER EXTRACT1: INCLUDING ONE CASE OF PERNICIOUS ANEMIA FOLLOWING GASTRECTOMY. Ann Intern Med. ;7:353–368. doi: 10.7326/0003-4819-7-3-353
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Published: Ann Intern Med. 1933;7(3):353-368.
Hematology/Oncology, Red Cell Disorders.
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