GEZA DE TAKATS, M.D.; G. K. FENN, M.D.
One of us, with Cuthbert,1 reported that excision of the celiac ganglion in the dog resulted in a decided and persistent rise in sugar tolerance. Further analysis of the mechanism of the increase in tolerance showed that bilateral adrenal denervation or bilateral splanchnic section gave identical results.2 It was suggested in the first paper that the exclusion of sympathetic nerve impulses may bring about either an increased insulin production or a reduction in the insulin requirement. The susceptibility of the dogs to insulin was markedly increased after either of these operations, a fact previously observed by several workers.3
DE TAKATS G, FENN GK. BILATERAL SPLANCHNIC NERVE SECTION IN A JUVENILE DIABETIC(BILATERAL SPLANCHNIC NERVE SECTION IN A JUVENILE DIABETIC*). Ann Intern Med. 1933;7:422–430. doi: 10.7326/0003-4819-7-4-422
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Published: Ann Intern Med. 1933;7(4):422-430.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Neurology.
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