DONALD C. BEAVER, M.D.; JOHN DEJ. PEMBERTON, M.D.
For many years icterus has been known as a complication in cases of severe exophthalmic goiter. It has not been demonstrated, however, until fairly recently, that the liver may frequently undergo severe functional and anatomic changes in the syndrome of exophthalmic goiter.
Habershon,1 in 1874, reported a fatal case of exophthalmic goiter in which jaundice was a complicating feature. Sutcliff,2 in 1898, observed jaundice in an extraordinarily acute case of exophthalmic goiter. Eder,3 in 1906, reported three cases of exophthalmic goiter, in each of which jaundice was observed. He commented that Dieulafoy,4 in 1901, had described the association of jaundice
BEAVER DC, PEMBERTON JD. THE PATHOLOGIC ANATOMY OF THE LIVER IN EXOPHTHALMIC GOITER1. Ann Intern Med. ;7:687–708. doi: 10.7326/0003-4819-7-6-687
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Published: Ann Intern Med. 1933;7(6):687-708.
Endocrine and Metabolism, Gastroenterology/Hepatology, Liver Disease, Thyroid Disorders.
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