E. B. FREEMAN, M.D., F.A.C.P.
The cardiac disturbances associated with hyperthyroidism have long been recognized, as shown by the abundance of literature which has accumulated on the subject. Equally striking is the comparative dearth of publications dealing with the cardiac disturbances associated with hypothyroidism. In fact, nothing on this subject is to be found in the literature until 1918, when Zondek1 described under the term "Myxedema Heart" certain cardiac signs and symptoms observed in some myxedematous patients, namely: enlargement of the heart, feeble heart action, slow heart beat, normal blood pressure, and low amplitude of the auricular P- and the final ventricular T-waves in the
FREEMAN EB. CHRONIC PERICARDIAL EFFUSION IN MYXEDEMA: REPORT OF CASE(CHRONIC PERICARDIAL EFFUSION IN MYXEDEMA: REPORT OF CASE*). Ann Intern Med. 1934;7:1070–1079. doi: 10.7326/0003-4819-7-9-1070
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Published: Ann Intern Med. 1934;7(9):1070-1079.
Cardiology, Endocrine and Metabolism, Pericardial Disease, Thyroid Disorders.
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