JACOB KLEIN, M.D.
For some time iodine has been emphasized as the most important factor in thyroid function. Iodine, however, is only one factor. Calcium is another element necessary to proper thyroid function. Various aspects of the problem have been discussed by Berry,1 Hellwig,2 Kottman,3 Abelin,4 and Juanita Thompson.5 As the latter has stated, both calcium and iodine exert important influences on the thyroid, the normal function of which seems to depend on a proper relation between these two elements. Calcium in limestone areas has been stressed as an important factor in the causation of goiter, through a water supply rich in this
KLEIN J. THE EFFECT OF CALCIUM ON THE STORAGE OF COLLOID IN THE THYROID GLAND1. Ann Intern Med. ;7:1080–1083. doi: 10.7326/0003-4819-7-9-1080
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Published: Ann Intern Med. 1934;7(9):1080-1083.
Endocrine and Metabolism, Thyroid Disorders.
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