THOMAS WHEELDON, M.D.
Salts of ortho-iodoxybenzoic acid have been used clinically in the treatment of arthritis since 1926 when Young and Youmans1 reported the successful use of ammonium ortho-iodoxybenzoate, given intravenously, in 43 cases. Later Smith2 and Cottrell3 reported some success with the oral administration of calcium ortho-iodoxybenzoate, and this rapidly became the route of choice with the medical profession due to the fact that severe general reactions often followed the intravenous use of the ammonium salt.
For two years the writer has been using calcium ortho-iodoxybenzoate as a routine procedure in an investigation comprising a portion of the arthritic cases in his
WHEELDON T. THE USE OF CALCIUM ORTHO-IODOXYBENZOATE IN THE TREATMENT OF ARTHRITIS, WITH A DISCUSSION OF ITS POSSIBLE VALUE IN SOME OTHER ORTHOPEDIC CONDITIONS1. Ann Intern Med. 1934;7:1540–1547. doi: 10.7326/0003-4819-7-12-1540
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Published: Ann Intern Med. 1934;7(12):1540-1547.
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