D. MURRAY COWIE, M.D., F.A.C.P.; J. P. PARSONS, M.D.; K. LOWENBERG, M.D.
During the Michigan infantile paralysis epidemic of 1931 (figure 1) 125 cases came under our observation. Eighty-one of these were first seen in the so-called systemic or pre-paralytic stage, 44 in the paralytic stage. All of the systemic cases received either convalescent poliomyelitis serum, convalescent whole blood, adult whole blood or a combination of these by the various administration routes. Four of these developed paralysis. One was not under our control and is omitted from the total number, leaving 80 treated cases for analysis. Seventy-seven of these, or 96 per cent, did not develop paralysis. In the three patients developing
COWIE DM, PARSONS JP, LOWENBERG K. CLINICO-PATHOLOGIC OBSERVATIONS ON INFANTILE PARALYSIS: REPORT OF 125 ACUTE CASES WITH SPECIAL REFERENCE TO THE THERAPEUTIC USE OF CONVALESCENT AND ADULT BLOOD TRANSFUSIONS: THE POSSIBLE RELATION OF BLOOD GROUP TO THE SEVERITY OF THE DISEASE1. Ann Intern Med. ;8:521–551. doi: 10.7326/0003-4819-8-5-521
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Published: Ann Intern Med. 1934;8(5):521-551.
CNS Infections, Hematology/Oncology, Infectious Disease, Neurology.
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