N. W. JONES, M.D., F.A.C.P.; A. L. ROGERS, A.B.
There is a form of cardiovascular disease, seen more frequently than that due to syphilis, which is characterized by dilatation of the aorta and large vessels and a gross enlargement of the heart without special valvular defects. Its clinical course resembles that of syphilis in that symptoms referable to congestive failure make their appearance usually in the fourth and fifth decades of life. When aortic regurgitation is absent in cardiac syphilis a differential diagnosis between the two forms of heart disease may be quite impossible to make during life, and indeed at times a pathological anatomic differentiation may be impossible
JONES NW, ROGERS AL. THE INCIDENCE OF STREPTOCOCCAL INFECTION IN CARDIOVASCULAR SCLEROSIS1. Ann Intern Med. 1935;8:834–853. doi: 10.7326/0003-4819-8-7-834
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Published: Ann Intern Med. 1935;8(7):834-853.
Cardiology, Infectious Disease, Streptococcal Infections.
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