RICHARD D. FRIEDLANDER, M.D.; MORTON G. BROWN, M.D.
The clinical significance and the circulatory dynamic background of systolic murmurs have been subjects of considerable discussion for a great many years and probably will remain so.1, 2, 3, 4 The interpretations of such murmurs have varied from time to time. Once they were generally recognized as indicative of grave heart disease and later as having no meaning whatever.5 More recently a middle course has been taken by many of those interested in the subject.1, 6 The phenomenon is such that careful clinical observation in human beings offers the means of clarifying some of the confusion that exists. For this
FRIEDLANDER RD, BROWN MG. THE SYSTOLIC MURMUR: FURTHER OBSERVATIONS ON ITS CLINICAL SIGNIFICANCE 1. Ann Intern Med. ;8:893–899. doi: 10.7326/0003-4819-8-8-893
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Published: Ann Intern Med. 1935;8(8):893-899.
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