Almost everyone who reports any considerable number of cases representative of a certain disease mentions the incidence by sex. When significant differences exist, and when an explanation is attempted, it is almost invariably based on extraneous or environmental factors. Following this general plan pregnancy and obesity are said to cause the greater incidence of diseases of the gall-bladder among females, and alcoholism explains the predominance of males among those who have hepatic cirrhosis; the ratio of males to females in these two conditions, however, is about the same whether one is considering children or adults. It is apparent, therefore, that
HOW SEX AFFECTS THE INCIDENCE OF DISEASE AND MORTALITY1. Ann Intern Med. 1935;8:974–976. doi: 10.7326/0003-4819-8-8-974
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Published: Ann Intern Med. 1935;8(8):974-976.
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