THEODORE G. KLUMPP; SIMON KOLETSKY
In 1833 Beaumont1 noted, "In febrile diathesis, or predisposition, from whatever cause—obstructed perspiration, undue excitement by stimulating liquors, overloading the stomach with food—fear, anger, or whatever depresses or disturbs the nervous system—the villous coat becomes sometimes red and dry, at other times pale and moist, and loses its smooth and healthy appearance; the secretions become vitiated, greatly diminished, or entirely suppressed; the mucous coat scarcely perceptible; the follicles flat and flaccid, with secretion insufficient to protect the vascular and nervous papillae from irritation. . . . When considerable, and particularly, when there are corresponding symptoms of disease, no gastric
KLUMPP TG, KOLETSKY S. THE RELATION OF GASTRIC SECRETION TO HEMATOPOIESIS1. Ann Intern Med. ;8:991–1007. doi: 10.7326/0003-4819-8-9-991
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Published: Ann Intern Med. 1935;8(9):991-1007.
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