J. HAMILTON CRAWFORD, M.D., F.A.C.P.; W. S. MCDANIEL, M.D.
The use of mercury as a diuretic was advocated first by Jendrassik1 in 1886. He administered frequent small doses of calomel by mouth and by this means obtained in many cases a marked increase in urine volume. Gradually this form of treatment fell into more or less disuse as observers reported deleterious effects as a result of the mercury absorbed. In recent years, following the introduction of the complex organic compound of mercury, novasurol, first described by Saxl and Heilig2 in 1920, mercury has again assumed a prominent place in the treatment of edematous conditions. The favorable results which the
CRAWFORD JH, MCDANIEL WS. SOME OBSERVATIONS ON MERCURIAL DIURETICS1. Ann Intern Med. ;8:1266–1273. doi: 10.7326/0003-4819-8-10-1266
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Published: Ann Intern Med. 1935;8(10):1266-1273.
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