LOUIS FAUGERES BISHOP, M.D., F.A.C.P.; LOUIS FAUGERES BISHOP JR., M.D., F.A.C.P.; MAX TRUBEK, M.D.
The clinical recognition of erythremia should no longer offer difficulty. Its essential features have been identified by Vaquez,1 and the clinical syndrome made familiar since the descriptions by Osler.2, 3 The finding of an enlarged spleen in a patient with generalized "red" cyanosis should bring to mind the diagnosis of erythremia. More commonly, splenomegaly is associated with diseases characterized by anemia. The clinical distinction of polycythemia vera becomes difficult when we see the occasional patient suffering from this disease who presents himself in the late stages with anemia4 rather than polycythemia. The correct interpretation can then usually be made from
BISHOP LF, BISHOP LF, TRUBEK M. ERYTHREMIA1. Ann Intern Med. ;8:1602–1610. doi: 10.7326/0003-4819-8-12-1602
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Published: Ann Intern Med. 1935;8(12):1602-1610.
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