E. W. PHILLIPS, M.D., F.A.C.P.
The word "atopic" is used in this paper to characterize spontaneous acquired sensitization to a foreign protein. This is an extension of Coca's1 definition; but "allergy" means one thing to the allergist, another to the immunologist. For the purpose of the present discussion it is desirable to employ a term that excludes the delayed inflammatory reaction of the infected individual to tuberculoprotein, a reaction which students of tuberculosis generally describe as "allergic."
Atopic manifestations, especially hay fever, are often seen in cases of pulmonary tuberculosis. In 1925 I recorded the study,2 from the viewpoint of the allergist, of a series
PHILLIPS EW. ATOPIC ANNOYANCES IN THE COURSE OF PULMONARY TUBERCULOSIS1. Ann Intern Med. ;8:1649–1658. doi: 10.7326/0003-4819-8-12-1649
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Published: Ann Intern Med. 1935;8(12):1649-1658.
Infectious Disease, Mycobacterial Infections, Pulmonary Tuberculosis, Pulmonary/Critical Care.
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