JOSEPH B. WOLFFE, M.D.; HAROLD F. ROBERTSON, M.D.
The literature contains many case reports and a number of experimental studies of air embolism; but opinions still differ widely regarding its clinical significance and its mechanism.
Hobart Hare, in 1902, injected 60 c.c. of air into the jugular vein of a dog without the production of any symptoms whatever. In two patients, 2 to 3 c.c. of air were injected into the median basilic vein without ill effects. W. H. Luckett, in 1913, reported a case of air embolism in the lateral ventricles of the brain following a fracture of the skull in which the air was probably forced
WOLFFE JB, ROBERTSON HF. EXPERIMENTAL AIR EMBOLISM1. Ann Intern Med. ;9:162–165. doi: 10.7326/0003-4819-9-2-162
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Published: Ann Intern Med. 1935;9(2):162-165.
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