ALVAN L. BARACH, M.D., F.A.C.P.
The proposal of helium as a new therapeutic gas was based on the conception that its decreased specific gravity in relation to nitrogen would make a helium-oxygen mixture easier to breathe than a comparable nitrogen-oxygen mixture, such as occurs in air.1 The molecular weight of helium being 4, and that of nitrogen 28, the substitution of 80 per cent helium for 80 per cent nitrogen, with the oxygen concentration 20 per cent, would provide a respirable gas mixture which would have 33 per cent of the density of air (table 1). Utilizing the physical formula F equals MA, where
BARACH AL. THE USE OF HELIUM IN THE TREATMENT OF ASTHMA AND OBSTRUCTIVE LESIONS IN THE LARYNX AND TRACHEA1. Ann Intern Med. 1935;9:739–765. doi: 10.7326/0003-4819-9-6-739
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Published: Ann Intern Med. 1935;9(6):739-765.
Asthma, Pulmonary/Critical Care.
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