HOWARD F. ROOT, M.D., F.A.C.P.; THOMAS P. SHARKEY, M.D.
That arteriosclerosis occurs in excessive degree in diabetic patients has found general acceptance among American students. The importance of characteristic metabolic changes of diabetes in its causation was pointed out in the first study of Deaconess Hospital autopsy data by Root and Warren.1 Further reports by Joslin2 emphasized the clinical significance of arteriosclerotic complications of diabetes, and Warren3 summarized the pathologic data bearing upon arteriosclerosis in a large series of diabetics. Other aspects of this problem require investigation, such as (1) when does the excessive arteriosclerosis found in diabetic patients develop? (2) what are the characteristic steps in its progress?
ROOT HF, SHARKEY TP. ARTERIOSCLEROSIS AND HYPERTENSION IN DIABETES1. Ann Intern Med. ;9:873–882. doi: 10.7326/0003-4819-9-7-873
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Published: Ann Intern Med. 1936;9(7):873-882.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Hypertension.
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