HELMUTH ULRICH, M.D., F.A.C.P.; CARL E. TRAPP, M.D.; BEN VIDGOFF, M.D.
Inhalation of benzedrine (synthetic racemic benzyl-methyl carbinamine: C6H5CH2CHNH2CH31) for the relief of nasal congestion was found by one of us to be followed by sleeplessness, an experience that suggested the use of this method in the treatment of narcolepsy. Clinical trial showed, however, that inhalation of the drug produced very slight results, whereas oral medication was uniformly successful in preventing narcoleptic seizures. Six cases of narcolepsy have been treated by us and form the basis of this report. Prinzmetal and Bloomberg,2 also, in a recent report published since the inception of our study, found oral treatment with benzedrine to give
ULRICH H, TRAPP CE, VIDGOFF B. THE TREATMENT OF NARCOLEPSY WITH BENZEDRINE SULPHATE(THE TREATMENT OF NARCOLEPSY WITH BENZEDRINE SULPHATE*). Ann Intern Med. 1936;9:1213–1221. doi: 10.7326/0003-4819-9-9-1213
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Published: Ann Intern Med. 1936;9(9):1213-1221.
Pulmonary/Critical Care, Sleep Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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