G. L. WALDBOTT, M.D., F.A.C.P.; M. S. ASCHER, M.D.
In spite of many publications on the prevention of allergic shock following injections of pollen and serum, there remains a great deal of uncertainty concerning its causes and prevention. This is well illustrated by the fact that even those clinicians who are most experienced in the administration of hypodermic medication are still completely at loss to explain certain reactions. Piness,1 for instance, stated, in 1934, that despite the most careful gauging of doses there are reactions for which we are unable to account.
The importance in this connection of accidental intravenous injection of the allergen is not sufficiently stressed. In
WALDBOTT GL, ASCHER MS. THE RÔLE OF ACCIDENTAL PUNCTURE OF VEINS IN THE PRODUCTION OF ALLERGIC SHOCK1. Ann Intern Med. 1936;9:1232–1239. doi: 10.7326/0003-4819-9-9-1232
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Published: Ann Intern Med. 1936;9(9):1232-1239.
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