PAUL D. CRIMM, A.B., M.D., F.A.C.S.; J. W. STRAYER, A.B., M.D.
Phosphatase is an organic catalyst capable of either synthesizing or hydrolyzing any mono-ester of phosphoric acid. It was first discovered in rice and wheat bran by Suzuki, Yoshimura and Takaishi1 in 1907. (For a full review of the literature see Kay.2) It is present in large quantities in the intestinal mucosa, kidney and bone. Smaller quantities are found in practically all other organs and secretions. Fetal bone and the bone of young animals are richest in the enzyme, but the content diminishes as maturity is reached. The optimum pH in vitro is around 9—it is activated by Mg (Erdtman3) and
CRIMM PD, STRAYER JW. PHOSPHATASE CONTENT OF HUMAN SERUM IN PULMONARY TUBERCULOSIS FOLLOWING THE ADMINISTRATION OF VITAMIN D1. Ann Intern Med. ;9:1393–1397. doi: 10.7326/0003-4819-9-10-1393
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Published: Ann Intern Med. 1936;9(10):1393-1397.
Infectious Disease, Mycobacterial Infections, Pulmonary Tuberculosis, Pulmonary/Critical Care.
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