G. A. H.
Ever since its discovery almost fifteen years ago, many attempts have been made to render insulin still more effective as a clinical agent in the treatment of diabetes. These have taken two general directions: one, to find a more convenient and less difficult method of administration; and the other, to enhance its potency and to prolong the period of its physiological action. The chemical nature of this hormone, with its protein-like structure, probably renders it dependent for its physiological effects upon the molecular arrangement of its seven characteristic amino-acids. This structure also makes it vulnerable to attack by the digestive
H. GA. STUDIES ON INSULIN. Ann Intern Med. ;9:1437–1439. doi: 10.7326/0003-4819-9-10-1437
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Published: Ann Intern Med. 1936;9(10):1437-1439.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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