W. M. FOWLER, M.D.
The present concept of thrombopenic purpura as a definite syndrome has gradually been evolved and separated from the maze of hemorrhagic diseases. In the earliest fragmentary descriptions of purpura it was noted in association with the pestilent fevers,1 later it was found apart from these, and still more recently was separated as a distinct entity. A proper understanding of the condition, however, awaited the discovery of the blood platelets by Donne and Arnold2 and the observation by Denys3 and Hayem5 that the platelets were diminished in certain cases of purpura. This feature was subsequently verified by numerous observers and forms
FOWLER WM. THROMBOPENIC PURPURA; AN ANALYSIS OF 160 CASES1. Ann Intern Med. ;9:1475–1487. doi: 10.7326/0003-4819-9-11-1475
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Published: Ann Intern Med. 1936;9(11):1475-1487.
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