HARRY SHAY, M.D.; J. GERSHON-COHEN, M.D., M.SC. (Med.)
For the most part, anacidity has been regarded an interesting but scarcely serious medical curiosity. In the absence of gastric carcinoma, or of blood changes suggestive of Addisonian anemia, little consideration has been generally given the anacidity. In fact, since the work of Castle,1 it has progressively diminished in importance as a factor in anemia. Clinically, spectacular therapeutic results have been obtained from the administration of hydrochloric acid for the relief of vague, but distressing, digestive symptoms, or in the more obvious gastrogenous diarrhea. Experimentally, time and effort have been lavished upon the study of the response of the achlorhydric
SHAY H, GERSHON-COHEN J. A COMPARISON OF THE EFFECTIVENESS OF GLUTAMIC ACID HYDROCHLORIDE AND DILUTE HYDROCHLORIC ACID AS THE REPLACEMENT THERAPY IN ANACIDITY MEASURED BY FRACTIONAL GASTRIC ACID TITRATION AND HYDROGEN-ION CONCENTRATION CURVES(A COMPARISON OF THE EFFECTIVENESS OF GLUTAMIC ACID HYDROCHLORIDE AND DILUTE HYDROCHLORIC ACID AS THE REPLACEMENT THERAPY IN ANACIDITY MEASURED BY FRACTIONAL GASTRIC ACID TITRATION AND HYDROGEN-ION CONCENTRATION CURVES*). Ann Intern Med. 1936;9:1628–1638. doi: 10.7326/0003-4819-9-12-1628
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Published: Ann Intern Med. 1936;9(12):1628-1638.
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