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The work of Harrop1 and of Allers2 and others has shown that the adrenalectomized dog may be kept alive indefinitely without the use of cortical hormone by the administration of sufficient quantities of sodium in the forms of sodium chloride and of either sodium bicarbonate or sodium citrate. Recent work of Allers has indicated that if the potassium intake be kept to a very low level, these animals, maintained on a high sodium intake, will not only live but will show entirely normal plasma electrolyte levels.
Adrenalectomized animals maintained on this high sodium, low potassium régime have shown themselves very
THE IMPORTANCE OF POTASSIUM IN THE TREATMENT OF ADDISON'S DISEASE. Ann Intern Med. ;9:1752–1753. doi: 10.7326/0003-4819-9-12-1752
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Published: Ann Intern Med. 1936;9(12):1752-1753.
Adrenal Disorders, Endocrine and Metabolism.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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