SOLOMON GINSBURG, M.D.
A comprehensive survey of the available data reveals the following outstanding clinical characteristics of Hodgkin's disease.
1. Malignant and Protean Character of Hodgkin's Disease. Hodgkin's disease is a specific malignant disease which most frequently first manifests itself clinically by enlargement of the lymph glands and spleen accompanied by toxemia, anemia, wasting and cachexia. However, it is not confined to these lymphoid organs only. It is of historic interest to record that it was Hodgkin himself who was the first to make this observation, which has been repeatedly corroborated by numerous students of this disease. Indeed, more than half a century
GINSBURG S. LYMPHOSARCOMA AND HODGKIN'S DISEASE: CLINICAL CHARACTERISTICS1. Ann Intern Med. ;10:337–372. doi: 10.7326/0003-4819-10-3-337
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Published: Ann Intern Med. 1936;10(3):337-372.
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