Nitrous oxide-oxygen anesthesia is generally considered the safest of the general anesthetics. This belief is founded on a number of statistical studies of the anesthetic deaths occurring in very large series of general anesthesias from many countries. It is no doubt correct. Nevertheless most experienced anesthetists stress the need of particular watchfulness in the administration of nitrous oxide and the necessity of experience in its use before prolonged periods of deep surgical anesthesia are attempted.
To many internists who have had occasion to watch patients through nitrous oxide-oxygen anesthesias the reputed safety of this anesthetic must seem remarkable. Figures indicating
SEQUELAE OF ASPHYXIA DURING NITROUS OXIDE ANESTHESIA. Ann Intern Med. ;10:934–936. doi: 10.7326/0003-4819-10-6-934
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Published: Ann Intern Med. 1936;10(6):934-936.
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