D. J. STEPHENS, M.D.; NOLAN L. KALTREIDER, M.D.
Although venesection has been used for many years as an emergency measure in erythremia, its general use as a therapeutic agent in this disease has been considered contraindicated on the grounds that reduction of the blood level by this means would act as a further stimulus to erythrocyte production.1 Recent investigations, however, have indicated that this assumption may be unwarranted. Falconer2 has shown that the repeated removal of from 200 to 600 c.c. of blood at intervals of from a few days to three weeks did not increase the reticulocyte percentage above normal limits. Reimann and Breuer3 have studied the
STEPHENS DJ, KALTREIDER NL. THE THERAPEUTIC USE OF VENESECTION IN POLYCYTHEMIA1. Ann Intern Med. ;10:1565–1581. doi: 10.7326/0003-4819-10-10-1565
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Published: Ann Intern Med. 1937;10(10):1565-1581.
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