JOHN C. THOMPSON, F.A.C.P.
The fundamental work of Castle and his coworkers1, 2, 3, 4 proving that a definite antianemic substance, "Intrinsic Factor," is produced in the wall of the stomach, at present seems to be established beyond a reasonable doubt. The theories developed by the author on the basis of this monumental discovery have, however, been questioned by a number of observers. Some of these objections, notably those of Greenspon,5 have had to do with the nature of the antianemic material and the method of its production in the stomach. A more serious discrepancy, however, exists in the theory that this vital material
THOMPSON JC. THE HEMATOPOIETIC RESPONSE FOLLOWING ORAL ADMINISTRATION OF DESICCATED DUODENAL MUCOSA1. Ann Intern Med. ;11:39–56. doi: 10.7326/0003-4819-11-1-39
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Published: Ann Intern Med. 1937;11(1):39-56.
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