W. W. WESTERFELD; EDWARD A. DOISY
Active experimental work on the internal secretion of the ovary began with the demonstration of Knauer1 in 1899 that transplantation of the ovary from its normal site did not produce atrophy of the uterus. Following these experiments many other investigators have made important contributions to our knowledge in this field. Adler,2 Fellner,3 Hermann,4 Frank5 and others prepared extracts which were active in producing growth of the uterus.
Two other investigations played an important rôle in the development of this field. The first was the introduction (Allen and Doisy6) of the accurate and convenient method of assay by the vaginal
WESTERFELD WW, DOISY EA. KETONIC AND NON-KETONIC ESTROGENS1. Ann Intern Med. ;11:267–273. doi: 10.7326/0003-4819-11-2-267
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Published: Ann Intern Med. 1937;11(2):267-273.
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