J. H. MEANS, F.A.C.P.; S. HERTZ; J. LERMAN
That marked grades of malnutrition may result from thyrotoxicosis has been long known. In 1893 it was that Friedrich Müller1 noted the paradox of weight loss in the face of increased food intake and concluded therefrom that there must be in this disease an increased rate of katabolism.
Whether or not weight loss or general wasting will occur in Graves' disease depends on whether the appetite increase causes sufficient increase in the ingestion of total calories to offset the increased combustion. Compensatory hyperorexia we may call it. The bank balance, in other words, is determined by the relation of amounts
MEANS JH, HERTZ S, LERMAN J. NUTRITIONAL FACTORS IN GRAVES' DISEASE1. Ann Intern Med. ;11:429–436. doi: 10.7326/0003-4819-11-3-429
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Published: Ann Intern Med. 1937;11(3):429-436.
Endocrine and Metabolism, Thyroid Disorders.
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