PERRIN H. LONG, M.D.; ELEANOR A. BLISS, Sc.D.
The experimental observations 1, 2, 3, 4, 5, 6, 7 which have led to the use of sulphanilamide or its derivatives (chart 1) in the treatment of certain infectious diseases show that these chemicals have powerful chemotherapeutic effects in experimental infections. Clinical observations of their effects in human beings tend to confirm the laboratory results. In this communication we propose to discuss primarily the clinical application of these chemotherapeutic agents, and to detail the methods of their administration and the possible toxic effects which may become manifest in patients treated with sulphanilamide or its derivatives.
It is interesting to
LONG PH, BLISS EA. THE CLINICAL USE OF SULPHANILAMIDE AND ITS DERIVATIVES IN THE TREATMENT OF INFECTIOUS DISEASES1. Ann Intern Med. 1937;11:575–592. doi: 10.7326/0003-4819-11-4-575
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Published: Ann Intern Med. 1937;11(4):575-592.
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