JOSEPH C. AUB; ROBLEY D. EVANS; DARIUS M. GALLAGHER; DOROTHY M. TIBBETTS
In 1924 Blum, a dentist,1 and in 1925, Hoffman1 suggested that radium produced necrosis of the jaw. Our knowledge of the pernicious effects of stored radium salts in human beings dates essentially from the publications in 1925 of Castle, Drinker and Drinker2 and also Martland3 when necrosis of the jaw in workers who had absorbed radium salts was reported and discussed. Since that time, increasing numbers of similar cases have been recorded. Other abnormal clinical results of radium have been the appearance of severe anemias as well as a high percentage of osteogenic sarcoma, first described and discussed by Martland,3
AUB JC, EVANS RD, GALLAGHER DM, TIBBETTS DM. AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATT: EFFECTS OF TREATMENT ON RADIUM AND CALCIUM METABOLISM IN THE HUMAN BODY1. Ann Intern Med. ;11:1443–1463. doi: 10.7326/0003-4819-11-8-1443
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Published: Ann Intern Med. 1938;11(8):1443-1463.
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