The success of Goldberger and his associates in experimentally producing pellagra in man and its counterpart, black tongue, in dogs proved that a dietary deficiency plays an essential part in the production of these diseases. His demonstration that yeast, liver, and other foods rich in vitamin B2 (G) prevents and usually cures the disease indicates that the active substance is probably to be found in some portion of the vitamin B2 complex.
Certain facts, however, have led some investigators to believe that other factors are also concerned in the development of the disease. It seems probable that some individual predisposition
C. P. ADVANCES IN THE TREATMENT OF PELLAGRA. Ann Intern Med. ;11:1760–1762. doi: 10.7326/0003-4819-11-9-1760
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Published: Ann Intern Med. 1938;11(9):1760-1762.
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