JOHN L. CARMICHAEL, M.D.
The following cases are reported because the findings indicate that there may be a cause and effect relationship between hypothyroidism and hyperinsulinism, or at least that hypothyroidism may aggravate hyperinsulinism. Considerable experimental work has indicated a definite interrelationship between the secretion of the thyroid and that of the islet portion of the pancreas. It has been shown also clinically, that the injection of insulin changes the basal metabolic rate, but in a review of the literature available to us, no case report has been found indicating a definite relationship between hyperinsulinism and hypothyroidism. Tedstrom,1 however, reports a case with a
CARMICHAEL JL. HYPERINSULINISM ASSOCIATED WITH HYPOTHYROIDISM: TWO CASE REPORTS1. Ann Intern Med. 1938;11:1906–1911. doi: 10.7326/0003-4819-11-10-1906
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Published: Ann Intern Med. 1938;11(10):1906-1911.
Endocrine and Metabolism, Thyroid Disorders.
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