WILLIAM S. LOVE JR., M.D., F.A.C.P.; G. W. BRUGLER, M.D.; NATHAN WINSLOW, M.D.
In 1935, McGinn and White1 reported certain aberrations in the electrocardiograms derived from five patients suffering with pulmonary embolization. These deviations from normal were as follows:
1. Prominent S-wave and low origin of the T-wave in Lead I, the ST segment starting slightly below the baseline.
2. Staircase ascent of the ST segment from the S-wave to the T-wave in Lead II.
3. The presence of Q3, and inversion of the T-wave in this lead.
4. T-waves of opposite sign to normal in the precordial lead.
They considered it probable that the electrocardiographic changes consequent on pulmonary embolism were due
LOVE WS, BRUGLER GW, WINSLOW N. ELECTROCARDIOGRAPHIC STUDIES IN CLINICAL AND EXPERIMENTAL PULMONARY EMBOLIZATION1. Ann Intern Med. ;11:2109–2123. doi: 10.7326/0003-4819-11-12-2109
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Published: Ann Intern Med. 1938;11(12):2109-2123.
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