JOHN A. KOLMER, M.D., F.A.C.P.
Acute anterior poliomyelitis is still among the important diseases in which knowledge of the mechanism of infection, its mode of dissemination and the factors responsible for epidemics, as well as the nature of natural and acquired immunity, is quite incomplete and controversial in many particulars and especially in relation to methods of prophylaxis.
Twenty-eight years ago Flexner and Lewis1 first suggested that infection occurred through the upper respiratory tract and especially by way of the olfactory nerves. At least monkeys can be successfully inoculated by intranasal instillations of the virus and in spite of the technical difficulties this virus has
KOLMER JA. THE PRESENT STATUS OF METHODS FOR THE PROPHYLAXIS OF ACUTE ANTERIOR POLIOMYELITIS1. Ann Intern Med. ;12:95–105. doi: 10.7326/0003-4819-12-1-95
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Published: Ann Intern Med. 1938;12(1):95-105.
CNS Infections, Infectious Disease, Neurology.
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