VIRGIL H. MOON
A survey of recorded studies on anaphylaxis and on shock reveals the remarkable fact that neither of these conditions has been investigated by the methods of pathology. Probably this was because this type of circulatory phenomenon was interpreted as a functional disturbance having no morphologic basis. The belief that postmortem examinations in such conditions reveal no significant changes, apparently had not been questioned.
It has become apparent recently that a combination of the methods of pathology with those of physiology may produce pertinent evidence. It has been shown17a, b, 18 that shock, occurring clinically or produced experimentally in various ways
MOON VH. THE PATHOLOGY AND MECHANISM OF ANAPHYLAXIS1. Ann Intern Med. ;12:205–216. doi: 10.7326/0003-4819-12-2-205
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Published: Ann Intern Med. 1938;12(2):205-216.
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